Distal Muscular Dystrophy (DD)
Definition - A class of muscular dystrophies that primarily affect distal muscles, which are those of the lower arms, hands, lower legs and feet. Muscular dystrophies in general are a group of genetic, degenerative diseases primarily affecting voluntary muscles.
Cause - A mutation in any of at least eight genes that affect proteins necessary to the function of muscles.
Onset - childhood to adulthood
Symptoms - Weakness and wasting of muscles of the hands, forearms and lower legs.
Progression - Slow progression; not life-threatening.
Inheritance - May be autosomal dominant, meaning a faulty gene is inherited from one parent; or autosomal recessive, occurring when a faulty gene is inherited from each parent.